Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.

Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.

The disruption of cholesterol homeostasis leads to an increase in cholesterol levels which results in the development of cardiovascular disease. Mitogen Inducible Gene 6 (Mig-6) is an immediate early response gene that can be induced by various mitogens, stresses, and hormones. To identify the metab...

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Bibliographic Details
Main Authors: Bon Jeong Ku, Tae Hoon Kim, Jae Hee Lee, Eric D Buras, Lisa D White, Robert D Stevens, Olga R Ilkayeva, James R Bain, Christopher B Newgard, Francesco J DeMayo, Jae-Wook Jeong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422237?pdf=render

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http://europepmc.org/articles/PMC3422237?pdf=render

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