Pneumococcal extracellular vesicles mediate horizontal gene transfer via the transformation machinery

Pneumococcal extracellular vesicles mediate horizontal gene transfer via the transformation machinery

ABSTRACT Bacterial cells secrete extracellular vesicles (EVs), the function of which is a matter of intense investigation. Here, we show that the EVs secreted by the human pathogen Streptococcus pneumoniae (pneumococcus) are associated with bacterial DNA on their surface and can deliver this DNA to...

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Bibliographic Details
Main Authors: Sarah Werner Lass, Bailey E. Smith, Shaw Camphire, Rory A. Eutsey, Jojo A. Prentice, Saigopalakrishna S. Yerneni, Ashni Arun, Andrew A. Bridges, Jason W. Rosch, James F. Conway, Phil Campbell, N. Luisa Hiller
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mSphere
Subjects:
extracellular vesicle
Streptococcus pneumoniae
horizontal gene transfer
competence
transformation
antibiotic resistance
Online Access:https://journals.asm.org/doi/10.1128/msphere.00727-24

Internet

https://journals.asm.org/doi/10.1128/msphere.00727-24

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