Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi

Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi

Abstract Background The zoonotic simian parasite Plasmodium cynomolgi develops into replicating schizonts and dormant hypnozoites during the infection of hepatocytes and is used as a model organism to study relapsing malaria. The transcriptional profiling of P. cynomolgi liver stages was previously...

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Bibliographic Details
Main Authors: Gabriel Mitchell, Guglielmo Roma, Annemarie Voorberg-van der Wel, Martin Beibel, Anne-Marie Zeeman, Sven Schuierer, Laura Torres, Erika L. Flannery, Clemens H. M. Kocken, Sebastian A. Mikolajczak, Thierry T. Diagana
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Malaria Journal
Subjects:
Host response
Relapsing malaria
Schizonts
Hypnozoites
RNA sequencing
Liver cells
Online Access:https://doi.org/10.1186/s12936-022-04411-3

Internet

https://doi.org/10.1186/s12936-022-04411-3

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