Genopathomic profiling identifies signatures for immunotherapy response of lung adenocarcinoma via confounder-aware representation learning

Summary: Immunotherapy shows durable response but only in a subset of patients, and test for predictive biomarkers requires procedures in addition to routine workflow. We proposed a confounder-aware representation learning-based system, genopathomic biomarker for immunotherapy response (PITER), that...

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Bibliographic Details
Main Authors: Jiajun Deng, Jiancheng Yang, Likun Hou, Junqi Wu, Yi He, Mengmeng Zhao, Bingbing Ni, Donglai Wei, Hanspeter Pfister, Caicun Zhou, Tao Jiang, Yunlang She, Chunyan Wu, Chang Chen
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222016546