Effects of Some Antihypertensive Drugs on the Metabolism and Pharmacokinetics of Indapamide in Rats

Purpose. Indapamide, a non-thiazide antihypertensive diuretic agent, has been widely coadministered with other classes of antihypertensive agents to reach target systolic blood pressure. Indapamide is extensively metabolized by cytochromes P450. Interaction of indapamide and other antihypertensive d...

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Bibliographic Details
Main Authors: Fang Yan, Ying Hu, Bin Di, Ping Lei He, Guibin Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/11225