Fluorescein-Labeled Thiacalix[4]arenes as Potential Theranostic Molecules: Synthesis, Self-Association, and Antitumor Activity

Fluorescein-Labeled Thiacalix[4]arenes as Potential Theranostic Molecules: Synthesis, Self-Association, and Antitumor Activity

In this paper, a series of thiacalix[4]arenes were synthesized as potential theranostic molecules for antitumor therapy. We propose an original strategy for the regioselective functionalization of thiacalix[4]arene with a fluorescent label to obtain antiangiogenic agent mimetics. The aggregation pro...

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Bibliographic Details
Main Authors: Alan Akhmedov, Olga Terenteva, Evgenia Subakaeva, Pavel Zelenikhin, Ramilia Shurpik, Dmitriy Shurpik, Pavel Padnya, Ivan Stoikov
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceutics
Subjects:
thiacalixarene
antitumor activity
theranostics
fluorescein
quaternary ammonium salts
A549
Online Access:https://www.mdpi.com/1999-4923/14/11/2340

Internet

https://www.mdpi.com/1999-4923/14/11/2340

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