TZD-Based Hybrid Molecules Act as Dual Anti-<i>Mycobacterium tuberculosis</i> and Anti-<i>Toxoplasma gondii</i> Agents

TZD-Based Hybrid Molecules Act as Dual Anti-<i>Mycobacterium tuberculosis</i> and Anti-<i>Toxoplasma gondii</i> Agents

Two distinct intracellular pathogens, namely <i>Mycobacterium tuberculosis (Mtb)</i> and <i>Toxoplasma gondii (Tg),</i> cause major public health problems worldwide. In addition, serious and challenging health problems of co-infections of <i>Tg</i> with <i>M...

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Bibliographic Details
Main Authors: Katarzyna Dzitko, Barbara Kaproń, Agata Paneth, Adrian Bekier, Tomasz Plech, Piotr Paneth, Nazar Trotsko
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
thiazolidinedione
thiosemicarbazone
pyridine-4-carbohydrazone
dual anti-<i>Mycobacterium tuberculosis</i> and anti-<i>Toxoplasma gondii</i> mode of action
in vitro and in vivo toxicity
PAMPA-BBB assay
Online Access:https://www.mdpi.com/1422-0067/24/3/2069

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https://www.mdpi.com/1422-0067/24/3/2069

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