Aberrations of DNA Repair Pathways in Prostate Cancer: Future Implications for Clinical Practice?

Aberrations of DNA Repair Pathways in Prostate Cancer: Future Implications for Clinical Practice?

Patients who are carriers of inherited mutations in essential component of DNA repair pathways have a significantly higher lifetime risk for developing cancer compared to the population of reference. Recent advances in DNA next-generation sequencing technology have allowed screening for carriers of...

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Bibliographic Details
Main Authors: Orazio Caffo, Antonello Veccia, Stefania Kinspergher, Mimma Rizzo, Francesca Maines
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
prostate cancer
PARP inhibitors
BRCA1
BRCA2
olaparib
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00071/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2018.00071/full

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