Rapid Complexation of Aptamers by Their Specific Antidotes

Rapid Complexation of Aptamers by Their Specific Antidotes

Nucleic acid ligands, aptamers, harbor the unique characteristics of small molecules and antibodies. The specificity and high affinity of aptamers enable their binding to different targets, such as small molecules, proteins, or cells. Chemical modifications of aptamers allow increased bioavailabilit...

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Bibliographic Details
Main Authors: Heidi Stoll, Heidrun Steinle, Nadja Wilhelm, Ludmilla Hann, Silju-John Kunnakattu, Miwako Narita, Christian Schlensak, Hans P. Wendel, Meltem Avci-Adali
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Molecules
Subjects:
aptamers
antidote
therapeutics
complexation
Online Access:http://www.mdpi.com/1420-3049/22/6/954

Internet

http://www.mdpi.com/1420-3049/22/6/954

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