Identification of gene variants in 130 Han Chinese patients with hypospadias by targeted next‐generation sequencing

Identification of gene variants in 130 Han Chinese patients with hypospadias by targeted next‐generation sequencing

Abstract Background Hypospadias is a common congenital malformation of male external genitalia, which mainly manifests as an abnormal urethral opening on the ventral side of the penis. The etiology and clinical phenotype of hypospadias is highly heterogeneous, and its clinical diagnosis is challengi...

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Bibliographic Details
Main Authors: Wanyu Zhang, Jinxiu Shi, Chenhui Zhang, Xincheng Jiang, Junqi Wang, Wei Wang, Defen Wang, Jihong Ni, Lifen Chen, Wenli Lu, Yuan Xiao, Weijing Ye, Zhiya Dong
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
candidate gene
hypospadias
next‐generation sequencing
pathogenic genes
Online Access:https://doi.org/10.1002/mgg3.827

Internet

https://doi.org/10.1002/mgg3.827

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