METTL16 predicts a favorable outcome and primes antitumor immunity in pancreatic ductal adenocarcinoma

METTL16 predicts a favorable outcome and primes antitumor immunity in pancreatic ductal adenocarcinoma

Pancreatic carcinogenesis is a complicated and multi-step process. It is substantially assisted by N6-methyladenosine (m6A) RNA modification, especially when mutations of driver genes (KRAS, TP53, CDKN2A, and SMAD4) occur. However, the underlying mechanism remains obscure. In this research, we ident...

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Bibliographic Details
Main Authors: Liting Lu, Dandan Zheng, Junchi Qu, Yanyan Zhuang, Juanfei Peng, Sihua Lan, Shineng Zhang, Fengting Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
pancreatic ductal adenocarcinoma
METTL16
prognostic biomarker
tumor microenvironment
N6-methyladenosine
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.759020/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.759020/full

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