Abnormal TNS3 gene methylation in patients with congenital scoliosis

Abnormal TNS3 gene methylation in patients with congenital scoliosis

Abstract Background Congenital scoliosis (CS) is a congenital deformity of the spine resulting from abnormal and asymmetrical development of vertebral bodies during pregnancy. However, the etiology and mechanism of CS remain unclear. Epigenetics is the study of heritable variations in gene expressio...

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Bibliographic Details
Main Authors: YuanTao Wu, Hong-qi Zhang, Mingxing Tang, Chaofeng Guo, Shaohua Liu, Jiong Li, Yunjia Wang, Lige Xiao, Guanteng Yang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Musculoskeletal Disorders
Subjects:
Congenital scoliosis
Genome methylation sequencing
Methylation level of the promoter region
MethylTarget
TNS3
Immunohistochemistry
Online Access:https://doi.org/10.1186/s12891-022-05730-x

Internet

https://doi.org/10.1186/s12891-022-05730-x

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