Enhancement of Cisplatin Nephrotoxicity by Morphine and Its Attenuation by the Opioid Antagonist Naltrexone

Enhancement of Cisplatin Nephrotoxicity by Morphine and Its Attenuation by the Opioid Antagonist Naltrexone

Nephrotoxicity is a major side effect of cisplatin, a widely used chemotherapy agent. Morphine and other opioids are also used extensively in different types of cancer for the clinical management of pain associated with local or metastatic neoplastic lesions. In addition to its analgesic effects, mo...

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Bibliographic Details
Main Authors: Atefeh Aminian, Shiva Javadi, Reza Rahimian, Ahmad Reza Dehpour, Fahimeh Asadi Amoli, Payman Moghaddas, Shahram Ejtemaei Mehr
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-07-01
Series:Acta Medica Iranica
Subjects:
Cisplatin
Morphine
Naltrexone
Antioxidant
Nephrotoxicity
Immunomodulatory
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/4963

Internet

https://acta.tums.ac.ir/index.php/acta/article/view/4963

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