Asperuloside regulates the proliferation, apoptosis, and differentiation of chronic myeloid leukemia cell line K562 through the RAS/MEK/ERK pathway

Asperuloside regulates the proliferation, apoptosis, and differentiation of chronic myeloid leukemia cell line K562 through the RAS/MEK/ERK pathway

Context: Chronic myeloid leukemia (CML) is a malignant hematopoietic stem cell disease caused by excessive proliferation and abnormal differentiation of hematopoietic stem cells. Asperuloside (ASP) is considered to have good biological activity and may be a good anti-CML drug. Objective: This study...

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Bibliographic Details
Main Authors: Bingjie Zhao, Hong Che, Linlin Li, Lian Hu, Wenjing Yi, Li Xiao, Songshan Liu, Zhufa Hou
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
RNA-seq
Iridoid
Pharmacological research
Anti-cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023107882

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http://www.sciencedirect.com/science/article/pii/S2405844023107882

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