Revealing the transcriptional heterogeneity of organ‐specific metastasis in human gastric cancer using single‐cell RNA Sequencing

Revealing the transcriptional heterogeneity of organ‐specific metastasis in human gastric cancer using single‐cell RNA Sequencing

Abstract Background Deciphering intra‐ and inter‐tumoural heterogeneity is essential for understanding the biology of gastric cancer (GC) and its metastasis and identifying effective therapeutic targets. However, the characteristics of different organ‐tropism metastases of GC are largely unknown. Me...

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Bibliographic Details
Main Authors: Haiping Jiang, Dingyi Yu, Penghui Yang, Rongfang Guo, Mei Kong, Yuan Gao, Xiongfei Yu, Xiaoyan Lu, Xiaohui Fan
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Clinical and Translational Medicine
Subjects:
gastric cancer
HLA‐E‐KLRC1/KLRC2
metastasis
single‐cell RNA sequencing
tumoural heterogeneity
Online Access:https://doi.org/10.1002/ctm2.730

Internet

https://doi.org/10.1002/ctm2.730

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