Cepharanthine sensitizes triple-negative breast cancer cells to doxorubicin and inhibits cell proliferation

Cepharanthine sensitizes triple-negative breast cancer cells to doxorubicin and inhibits cell proliferation

Objective To explore the molecular mechanism by which cepharanthine (CEP) sensitizes triple-negative breast cancer cells to doxorubicin (DOX) chemotherapy. Methods The triple-negative breast cancer cell lines MDA-MB-231 and MDA-MB-468 were treated with CEP (2, 4, 6, 8, or 10 μmol/L) alone, DOX (0.2,...

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Bibliographic Details
Main Authors: ZHANG Yanhao, HU Jinjiao, GAO Ning
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2019-11-01
Series:Di-san junyi daxue xuebao
Subjects:
cepharanthine
doxorubicin
triple-negative breast cancer
mitophagy
oxidative stress
cell proliferation
apoptosis
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201905138.htm

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http://aammt.tmmu.edu.cn/Upload/rhtml/201905138.htm

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