The direct STAT3 inhibitor 6-ethoxydihydrosanguinarine exhibits anticancer activity in gastric cancer

Signal transducer and activator of transcription 3 (STAT3) plays a key role in promoting tumor malignant progression. Suppression of hyperactivated STAT3 signaling has emerged as a potential therapeutic strategy for many cancer types. In this study, the effect of 6-ethoxydihydrosanguinarine (6-EDS),...

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Bibliographic Details
Main Authors: Xuewen Liu, Xin Jin, Hongling Ou, Chen Qian, Hui Wu, Chunmei Zuo, Yuliang Ren, Miaoxin Fu, Te Zhang, Liang Zhang, Yuan Si, Ying Liu
Format: Article
Language:English
Published: Compuscript Ltd 2022-10-01
Series:Acta Materia Medica
Subjects:
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2022-0027