Electrophysiological basis of cardiac arrhythmia in a mouse model of myotonic dystrophy type 1

Electrophysiological basis of cardiac arrhythmia in a mouse model of myotonic dystrophy type 1

Introduction: Myotonic dystrophy type 1 (DM1) is a multisystemic genetic disorder caused by the increased number of CTG repeats in 3′ UTR of Dystrophia Myotonia Protein Kinase (DMPK) gene. DM1 patients experience conduction abnormalities as well as atrial and ventricular arrhythmias with increased s...

Full description

Bibliographic Details
Main Authors: Vamsi Krishna Murthy Ginjupalli, Michael Cupelli, Jean-Baptiste Reisqs, Yvonne Sleiman, Nabil El-Sherif, Genevieve Gourdon, Jack Puymirat, Mohamed Chahine, Mohamed Boutjdir
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Physiology
Subjects:
myotonic dystrophy type 1
electrophysiology
ECG
arrhythmia
ion channels
conduction defects
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1257682/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1257682/full

Similar Items