Identification of functional regulatory elements in the human genome using pooled CRISPR screens
Abstract Background Genome-scale pooled CRISPR screens are powerful tools for identifying genetic dependencies across varied cellular processes. The vast majority of CRISPR screens reported to date have focused exclusively on the perturbation of protein-coding gene function. However, protein-coding...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | BMC Genomics |
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Online Access: | https://doi.org/10.1186/s12864-020-6497-0 |