CK1δ stimulates ubiquitination‐dependent proteasomal degradation of ATF4 to promote chemoresistance in gastric Cancer

Abstract Chemoresistance remains a major obstacle to successful cancer therapy, especially for advanced cancers. It used to be recognised as a stable outcome resulting from genetic changes. However, recent studies showed that chemoresistance can also be unstable and reversible with the involvement o...

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Bibliographic Details
Main Authors: Lifeng Feng, Muchun Li, Xinyang Hu, Yiling Li, Liyuan Zhu, Miaoqin Chen, Qi Wei, Wenxia Xu, Qiyin Zhou, Weikai Wang, Dingwei Chen, Xian Wang, Hongchuan Jin
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.587