Metabolomics profiling of AKT/c-Met-induced hepatocellular carcinogenesis and the inhibitory effect of Cucurbitacin B in mice

Metabolomics profiling of AKT/c-Met-induced hepatocellular carcinogenesis and the inhibitory effect of Cucurbitacin B in mice

Hepatocellular carcinoma (HCC), the most common kind of liver cancer, accounts for the majority of liver cancer diagnoses and fatalities. Clinical aggressiveness, resistance to traditional therapy, and a high mortality rate are all features of this disease. Our previous studies have shown that co-ac...

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Bibliographic Details
Main Authors: Xiangyu Ji, Xin Chen, Lei Sheng, Dongjie Deng, Qi Wang, Yan Meng, Zhenpeng Qiu, Baohui Zhang, Guohua Zheng, Junjie Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
hepatocellular carcinoma
AKT/c-Met
Cucurbitacin B
metabolomics
UPLC-Q-TOF-MS/MS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1009767/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1009767/full

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