Impact of radiotherapy to the primary tumor on the efficacy of pembrolizumab for patients with advanced urothelial cancer: A preliminary study

Impact of radiotherapy to the primary tumor on the efficacy of pembrolizumab for patients with advanced urothelial cancer: A preliminary study

Abstract Radiotherapy plus immune checkpoint inhibitors can potentially induce synergistic antitumor immune responses. However, little clinical evidence is established regarding their combination therapy. Here, we aimed to assess whether radiotherapy to the primary tumor impacts on the efficacy of p...

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Bibliographic Details
Main Authors: Hiroshi Fukushima, Toshiki Kijima, Shohei Fukuda, Shingo Moriyama, Sho Uehara, Yosuke Yasuda, Hajime Tanaka, Soichiro Yoshida, Minato Yokoyama, Yoh Matsuoka, Kazutaka Saito, Nobuaki Matsubara, Noboru Numao, Yasuyuki Sakai, Takeshi Yuasa, Hitoshi Masuda, Junji Yonese, Yukio Kageyama, Yasuhisa Fujii
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Cancer Medicine
Subjects:
carcinoma, transitional cell
immunotherapy
pembrolizumab
radiotherapy
treatment outcome
Online Access:https://doi.org/10.1002/cam4.3445

Internet

https://doi.org/10.1002/cam4.3445

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