Mobilized Multipotent Hematopoietic Progenitors Promote Expansion and Survival of Allogeneic Tregs and Protect Against Graft Versus Host Disease

Mobilized Multipotent Hematopoietic Progenitors Promote Expansion and Survival of Allogeneic Tregs and Protect Against Graft Versus Host Disease

Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) is routinely performed with peripheral blood stem cells (PBSCs) mobilized by injection of G-CSF, a growth factor which not only modulates normal hematopoiesis but also induces diverse immature regulatory cells. Based on our previous evid...

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Bibliographic Details
Main Authors: Maud D’Aveni, Anne-Béatrice Notarantonio, Viviane A. Agbogan, Allan Bertrand, Guillemette Fouquet, Pauline Gastineau, Meriem Garfa-Traoré, Marcelo De Carvalho, Olivier Hermine, Marie-Thérèse Rubio, Flora Zavala
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
allogeneic HSCT
graft versus host disease
mobilization
multipotent progenitors
regulatory T cells
expansion
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.607180/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.607180/full

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