Identification of effective diagnostic biomarker and immune cell infiltration characteristics in acute liver failure by integrating bioinformatics analysis and machine-learning strategies

Identification of effective diagnostic biomarker and immune cell infiltration characteristics in acute liver failure by integrating bioinformatics analysis and machine-learning strategies

Background: To determine effective biomarkers for the diagnosis of acute liver failure (ALF) and explore the characteristics of the immune cell infiltration of ALF.Methods: We analyzed the differentially expressed genes (DEGs) between ALF and control samples in GSE38941, GSE62029, GSE96851, GSE12065...

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Bibliographic Details
Main Authors: Mengqin Yuan, Lichao Yao, Xue Hu, Yingan Jiang, Lanjuan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
acute liver failure
lasso logistic regression
SVM-RFE
diagnostic biomarker
immune cell infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1004912/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.1004912/full

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