Acquiring of photosensitivity by Mycobacterium tuberculosis in vitro and inside infected macrophages is associated with accumulation of endogenous Zn–porphyrins

Abstract Mycobacterium tuberculosis (Mtb) is able to transition into a dormant state, causing the latent state of tuberculosis. Dormant mycobacteria acquire resistance to all known antibacterial drugs and can survive in the human body for decades before becoming active. In the dormant forms of M. tu...

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Bibliographic Details
Main Authors: Margarita O. Shleeva, Irina A. Linge, Ivan A. Gligonov, Galina N. Vostroknutova, Denis M. Shashin, Andrey M. Tsedilin, Alexander S. Apt, Arseny S. Kaprelyants, Alexander P. Savitsky
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51227-z