Synergistic up-regulation of CXCL10 by virus and IFN γ in human airway epithelial cells.

Synergistic up-regulation of CXCL10 by virus and IFN γ in human airway epithelial cells.

Airway epithelial cells are the first line of defense against viral infections and are instrumental in coordinating the inflammatory response. In this study, we demonstrate the synergistic stimulation of CXCL10 mRNA and protein, a key chemokine responsible for the early immune response to viral infe...

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Bibliographic Details
Main Authors: Karen L Oslund, Xu Zhou, Boram Lee, Lingxiang Zhu, Trang Duong, Robert Shih, Nicole Baumgarth, Li-Yin Hung, Reen Wu, Yin Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4102466?pdf=render

Internet

http://europepmc.org/articles/PMC4102466?pdf=render

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