Single-cell RNA sequencing reveals cell type-specific immune regulation associated with human neuromyelitis optica spectrum disorder

Single-cell RNA sequencing reveals cell type-specific immune regulation associated with human neuromyelitis optica spectrum disorder

IntroductionOne rare type of autoimmune disease is called neuromyelitis optica spectrum disorder (NMOSD) and the peripheral immune characteristics of NMOSD remain unclear.MethodsHere, single-cell RNA sequencing (scRNA-seq) is used to characterize peripheral blood mononuclear cells from individuals w...

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Bibliographic Details
Main Authors: Yushu Jiang, Shuhua Dai, Rui Pang, Lingzhi Qin, Milan Zhang, Huiqin Liu, Xiaojuan Wang, Jiewen Zhang, Gongxin Peng, Yongchao Wang, Wei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
neuromyelitis optica spectrum disorder
peripheral blood mononuclear cell
single-cell RNA sequencing
B cell
T cell
myeloid cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1322125/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1322125/full

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