A Validated LC-MS/MS Method for Performing Belatacept Drug Monitoring in Renal Transplantation

A Validated LC-MS/MS Method for Performing Belatacept Drug Monitoring in Renal Transplantation

Belatacept, a CTLA4-Ig, was designed to prevent rejection and graft loss in kidney transplant recipients. This immunotherapy showed a long-term clinical benefit mainly on renal function and better glycemic control but was also associated with a higher number of severe infectious diseases, particular...

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Bibliographic Details
Main Authors: Stéphanie Chhun, Mathieu Trauchessec, Sophie Melicine, Frédéric Nicolas, Agathe Miele, Srboljub Lukic, Estelle Vilain, Lucile Amrouche, Dorothée Lebert, Dany Anglicheau, Eric Tartour, Julien Zuber
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomedicines
Subjects:
belatacept
CTLA4-Ig
transplantation
kidney
pharmacokinetic
Online Access:https://www.mdpi.com/2227-9059/11/11/2955

Internet

https://www.mdpi.com/2227-9059/11/11/2955

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