Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia

Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia

Summary: Microglia-mediated synaptic plasticity after CNS injury varies depending on injury severity, but the mechanisms that adjust synaptic plasticity according to injury differences are largely unknown. This study investigates differential actions of microglia on essential spinal motor synaptic c...

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Bibliographic Details
Main Authors: Travis M. Rotterman, Zoë Haley-Johnson, Tana S. Pottorf, Tavishi Chopra, Ethan Chang, Shannon Zhang, William M. McCallum, Sarah Fisher, Haley Franklin, Myriam Alvarez, Timothy C. Cope, Francisco J. Alvarez
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Neuroscience
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724001049

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http://www.sciencedirect.com/science/article/pii/S2211124724001049

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