JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension
Abstract Pulmonary arterial hypertension (PAH) is a chronic disorder characterized by hyperproliferation of pulmonary arterial smooth muscle cells (PASMCs). JMJD1C, a member of the Jumonji domain containing C (JMJC) histone demethylase family, contributes to cardiovascular dysfunction. However, the...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-03-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01390-5 |