Requirement of Cholesterol for Calcium‐Dependent Vesicle Fusion by Strengthening Synaptotagmin‐1‐Induced Membrane Bending

Abstract Cholesterol is essential for neuronal activity and function. Cholesterol depletion in the plasma membrane impairs synaptic transmission. However, the molecular mechanisms by which cholesterol deficiency leads to defects in vesicle fusion remain poorly understood. Here, it is shown that chol...

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Bibliographic Details
Main Authors: Houda Yasmine Ali Moussa, Kyung Chul Shin, Janarthanan Ponraj, Soo Jin Kim, Je‐Kyung Ryu, Said Mansour, Yongsoo Park
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202206823