A stochastic model of active zone material mediated synaptic vesicle docking and priming at resting active zones
Abstract Synaptic vesicles (SVs) fuse with the presynaptic membrane (PM) at specialized regions called active zones for synaptic transmission. SVs are associated with dense aggregates of macromolecules called active zone material (AZM) that has been thought to be involved in SV release. However, its...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-00360-z |