A stochastic model of active zone material mediated synaptic vesicle docking and priming at resting active zones

Abstract Synaptic vesicles (SVs) fuse with the presynaptic membrane (PM) at specialized regions called active zones for synaptic transmission. SVs are associated with dense aggregates of macromolecules called active zone material (AZM) that has been thought to be involved in SV release. However, its...

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Bibliographic Details
Main Authors: Jae Hoon Jung, Sebatian Doniach
Format: Article
Language:English
Published: Nature Portfolio 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00360-z