DNA nanovaccines prepared using LemA antigen protect Golden Syrian hamsters against Leptospira lethal infection

BACKGROUND Nanoparticles (NPs) are viable candidates as carriers of exogenous materials into cells via transfection and can be used in the DNA vaccination strategy against leptospirosis. OBJECTIVES We evaluated the efficiency of halloysite clay nanotubes (HNTs) and amine-functionalised multi-wall...

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Bibliographic Details
Main Authors: Thaís Larré Oliveira, Kátia Leston Bacelo, Karine Maciel Forster, Vinicius Ilha, Oscar Endrigo Rodrigues, Daiane D Hartwig
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2020-04-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100311&tlng=en