Single-arm, phase II study of intra-arterial chemotherapy plus total neoadjuvant therapy to optimise complete response in distal rectal cancer: a study protocol

Introduction Organ preservation is now considered an acceptable alternative option in distal rectal cancer patients with clinical complete response (cCR) after neoadjuvant chemoradiation (CRT). But the cCR rate is low and about one-third of tumour will regrow, which requires more effective local tre...

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Bibliographic Details
Main Authors: Cheng Lin, Jie Lin, Wenpeng Huang, Puda Huang, Houji Guo, Zanyi Huang, Mingwei Wei, Junyu Guo, Yepeng Li, Biao Luo, Lixue Wang
Format: Article
Language:English
Published: BMJ Publishing Group 2023-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/10/e075023.full