Progression free survival of myeloma patients who become IFE-negative correlates with the detection of residual monoclonal free light chain (FLC) by mass spectrometry

Abstract Deeper responses are associated with improved survival in patients being treated for myeloma. However, the sensitivity of the current blood-based assays is limited. Historical studies suggested that normalisation of the serum free light chain (FLC) ratio in patients who were negative by imm...

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Bibliographic Details
Main Authors: H. V. Giles, M. T. Drayson, B. Kishore, C. Pawlyn, M. Kaiser, G. Cook, R. de Tute, R. G. Owen, D. Cairns, T. Menzies, F. E. Davies, G. J. Morgan, G. Pratt, G. H. Jackson
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-024-00995-y