mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study.

Differences in mRNA expression levels have been observed in failing versus non-failing human hearts for several membrane channel proteins and accessory subunits. These differences may play a causal role in electrophysiological changes observed in human heart failure and atrial fibrillation, such as...

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Bibliographic Details
Main Authors: John Walmsley, Jose F Rodriguez, Gary R Mirams, Kevin Burrage, Igor R Efimov, Blanca Rodriguez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3577832?pdf=render