Monoclonal antibodies constructed from COVID-19 convalescent memory B cells exhibit potent binding activity to MERS-CoV spike S2 subunit and other human coronaviruses

Monoclonal antibodies constructed from COVID-19 convalescent memory B cells exhibit potent binding activity to MERS-CoV spike S2 subunit and other human coronaviruses

IntroductionThe Middle East respiratory syndrome coronavirus (MERS-CoV) and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are two highly contagious coronaviruses causing MERS and COVID-19, respectively, without an effective antiviral drug and a long-lasting vaccine. Approaches for...

Full description

Bibliographic Details
Main Authors: Yuan Peng, Yongcheng Liu, Yabin Hu, Fangfang Chang, Qian Wu, Jing Yang, Jun Chen, Shishan Teng, Jian Zhang, Rongzhang He, Youchuan Wei, Mihnea Bostina, Tingrong Luo, Wenpei Liu, Xiaowang Qu, Yi-Ping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
COVID-19
convalescents
monoclonal antibody
coronavirus
middle eastern respiratory syndrome coronavirus
spike protein
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1056272/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1056272/full

Similar Items