Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomics

Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomics

Abstract Gonad somatic cells acquire sex-specific fates during sex determination. In XX gonad, a subset of somatic cells expresses Foxl2 after sex determination which is considered the progenitor of granulosa cells. However, whether these cells also contribute to other cell types at later developmen...

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Bibliographic Details
Main Authors: Jingjing Zhou, Xiangxiang Jiang, Haowei Wu, Lianjun Zhang, Min Chen, Zhiming Shen, Xudong Guo, Hongmei Wang, Fei Gao
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00492-1

Internet

https://doi.org/10.1038/s41421-022-00492-1

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