Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomics
Abstract Gonad somatic cells acquire sex-specific fates during sex determination. In XX gonad, a subset of somatic cells expresses Foxl2 after sex determination which is considered the progenitor of granulosa cells. However, whether these cells also contribute to other cell types at later developmen...
Main Authors: | Jingjing Zhou, Xiangxiang Jiang, Haowei Wu, Lianjun Zhang, Min Chen, Zhiming Shen, Xudong Guo, Hongmei Wang, Fei Gao |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-12-01
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Series: | Cell Discovery |
Online Access: | https://doi.org/10.1038/s41421-022-00492-1 |
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