The correlation between electronic structure and antitumor activity of a seletive focal adhesion kinase inhibitors
Focal Adhesion Kinase (FAK) is a non-tyrosine kinase responsible to phosphorylate other enzymes associated with signal transduction. This biochemical process plays an important role to control cancer. FAK is found overexpressed in the organism during metastasis. Since FAK may be involved in the inva...
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| Format: | Article |
| Language: | English |
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Universidade Estadual Paulista
2018-10-01
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| Series: | Eclética Química |
| Online Access: | https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/165 |