The correlation between electronic structure and antitumor activity of a seletive focal adhesion kinase inhibitors

The correlation between electronic structure and antitumor activity of a seletive focal adhesion kinase inhibitors

Focal Adhesion Kinase (FAK) is a non-tyrosine kinase responsible to phosphorylate other enzymes associated with signal transduction. This biochemical process plays an important role to control cancer. FAK is found overexpressed in the organism during metastasis. Since FAK may be involved in the inva...

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Bibliographic Details
Main Author:	Daniel Augusto Barra de Oliveira
Format:	Article
Language:	English
Published:	Universidade Estadual Paulista 2018-10-01
Series:	Eclética Química
Online Access:	https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/165

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