Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women

Abstract Background Studies investigating breast cancer polygenic risk score (PRS) in Chinese women are scarce. The objectives of this study were to develop and validate PRSs that could be used to stratify risk for overall and subtype-specific breast cancer in Chinese women, and to evaluate the perf...

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Bibliographic Details
Main Authors: Can Hou, Bin Xu, Yu Hao, Daowen Yang, Huan Song, Jiayuan Li
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-09425-3