Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women
Abstract Background Studies investigating breast cancer polygenic risk score (PRS) in Chinese women are scarce. The objectives of this study were to develop and validate PRSs that could be used to stratify risk for overall and subtype-specific breast cancer in Chinese women, and to evaluate the perf...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-04-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-022-09425-3 |