YAP mechanotransduction under cyclic mechanical stretch loading for mesenchymal stem cell osteogenesis is regulated by ROCK

YAP mechanotransduction under cyclic mechanical stretch loading for mesenchymal stem cell osteogenesis is regulated by ROCK

While yes-associated protein (YAP) is now recognized as a potent mechanosensitive transcriptional regulator to affect cell growth and differentiation including the osteogenic transcription of mesenchymal stem cells (MSCs), most studies have reported the YAP mechanosensing of static mechanophysical c...

Full description

Bibliographic Details
Main Authors: Eunju Kim, Brandon D. Riehl, Tasneem Bouzid, Ruiguo Yang, Bin Duan, Henry J. Donahue, Jung Yul Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mechanical stretch loading
mesenchymal stem cell
osteogenesis
YAP
Hippo
ROCK
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1306002/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1306002/full

Similar Items