Molecular Docking, Synthesis and <i>In Vitro</i> Antiplasmodium Assay of Monoketone Curcumin Analogous from 2-Chlorobenzaldehyde

Molecular Docking, Synthesis and <i>In Vitro</i> Antiplasmodium Assay of Monoketone Curcumin Analogous from 2-Chlorobenzaldehyde

This research aimed to develop new curcumin analogous as antiplasmodium candidates. Six curcumin analogous (1-6) were proposed and docked against three Plasmodium falciparum receptors, namely PfENR, PfLDH, and PfATP6. The docking studies were carried out to predict the interaction among the compound...

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Bibliographic Details
Main Authors: Chessy Rima Mustika, Endang Astuti, Muhammad Idham Darussalam Mardjan
Format: Article
Language:English
Published: Department of Chemistry, Universitas Gadjah Mada 2024-06-01
Series:Indonesian Journal of Chemistry
Subjects:
aldol condensation
antiplasmodium
curcumin analogous
molecular docking
2-chlorobenzaldehyde
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/81122

Internet

https://jurnal.ugm.ac.id/ijc/article/view/81122

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