Proteomic Analysis of Exosomes Secreted from Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells

Proteomic Analysis of Exosomes Secreted from Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells

Extracellular vesicles (EVs) mediate many therapeutic effects of stem cells during cellular therapies. Bone marrow-derived mesenchymal stromal cells (BM-MSCs) were manufactured to overexpress the human antiprotease alpha-1 antitrypsin (hAAT) and studied to compare the EV production compared to lenti...

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Bibliographic Details
Main Authors: Hua Wei, Erica Green, Lauren Ball, Hongkuan Fan, Jennifer Lee, Charlie Strange, Hongjun Wang
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biology
Subjects:
mesenchymal stromal cells
alpah-1 antitrypsin
exosome
extracellular vesicles
therapy
Online Access:https://www.mdpi.com/2079-7737/11/1/9

Internet

https://www.mdpi.com/2079-7737/11/1/9

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