Inhibition of the calcium-sensing receptor by extracellular phosphate ions and by intracellular phosphorylation

As both a sensor of extracellular calcium (Ca2+o) concentration and a key controller of Ca2+o homeostasis, one of the most interesting properties of the calcium-sensing receptor (CaR) is its sensitivity to, and modulation by, ions and small ligands other than Ca2+. There is emerging evidence that ex...

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Bibliographic Details
Main Authors: Patricia P. Centeno, Lenah S. Binmahfouz, Khaleda Alghamdi, Donald T. Ward
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1154374/full