TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1

TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1

Abstract Background Prostate cancer (PCa) is a common malignant tumor of the genitourinary system. Clinical intervention in advanced PCa remains challenging. Tropomyosins 2 (TPM2) are actin-binding proteins and have been found as a biomarker candidate for certain cancers. However, no studies have ex...

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Bibliographic Details
Main Authors: Zonglong Wu, Liyuan Ge, Lulin Ma, Min Lu, Yimeng Song, Shaohui Deng, Peichen Duan, Tan Du, Yaqian Wu, Zhanyi Zhang, Shudong Zhang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cell & Bioscience
Subjects:
Prostate cancer
TPM2
PDLIM7
Hippo/YAP1 signaling pathway
Online Access:https://doi.org/10.1186/s13578-023-00993-w

Internet

https://doi.org/10.1186/s13578-023-00993-w

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