Ferroptosis Contributes to Isoflurane Neurotoxicity

The underlying mechanisms of isoflurane neurotoxicity in the developing brain remain unclear. Ferroptosis is a recently characterized form of programmed cell death distinct from apoptosis or autophagy, characterized by iron-dependent reactive oxygen species (ROS) generation secondary to failure of g...

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Bibliographic Details
Main Authors: Yimeng Xia, Xiaoyun Sun, Yan Luo, Creed M. Stary
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00486/full