The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity

The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity

Summary: The SARS-CoV-2 genome encodes a multitude of accessory proteins. Using comparative genomic approaches, an additional accessory protein, ORF3c, has been predicted to be encoded within the ORF3a sgmRNA. Expression of ORF3c during infection has been confirmed independently by ribosome profilin...

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Bibliographic Details
Main Authors: Hazel Stewart, Yongxu Lu, Sarah O’Keefe, Anusha Valpadashi, Luis Daniel Cruz-Zaragoza, Hendrik A. Michel, Samantha K. Nguyen, George W. Carnell, Nina Lukhovitskaya, Rachel Milligan, Yasmin Adewusi, Irwin Jungreis, Valeria Lulla, David A. Matthews, Stephen High, Peter Rehling, Edward Emmott, Jonathan L. Heeney, Andrew D. Davidson, James R. Edgar, Geoffrey L. Smith, Andrew E. Firth
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Molecular biology
Immunology
Microbiology
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223021570

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http://www.sciencedirect.com/science/article/pii/S2589004223021570

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